http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008219977-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c13f76b1017275bec770c6d5462bb570 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-065 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-445 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7068 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5355 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-496 |
| filingDate | 2006-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fcfac18e14ec11c90656b2f3f634f803 |
| publicationDate | 2008-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2008219977-A1 |
| titleOfInvention | Combinations Comprising Gemcitabine and Tyrosine Kinase Inhibitors for the Treatment of Pancreatic Cancer |
| abstract | The invention relates to a method of treating a warm-blooded animal having pancreatic cancer, in particular it relatesn to a method comprising administering to the warm-blooded animal having pancreatic cancer a dual inhibitor of the epidermal growth factor receptor (EGF-R) tyrosine kinase activity and the vascular endothelial growth factor receptor (VEGF-R) tyrosine kinase activity, to a method comprising administering to the warm-blooded animal having pancreatic cancer a combination comprising (a) a compound which decrease the activity of the EGF and (b) a compound which decreases the activity of VEGF, to a combination comprising (a) a dual inhibitor of the EGF-R tyrosine kinase activity and the VEGF-R tyrosine kinase activity or, alternatively, a compound which decrease the activity of the EGF and a compound which decreases the activity of VEGF and (b) at least one compound selected from an inhibitor of the platelet derived growth factor receptor (PDGF-R) tyrosine kinase activity and antineoplastic anti-metabolites; to a method of treating a warm-blooded animal having pancreatic cancer comprising administering to the warm-blooded animal said combination; to the use of such a combination for the preparation of a medicament for the treatment of pancreatic cancer; and to a commercial package or product comprising such a combination together with instructions for the treatment of pancreatic cancer. |
| priorityDate | 2005-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 285.