Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_958fe5e7f345ca0a091332d5afd38538 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2b198ae79a4caca999d5761d1c85c255 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e906fe72d8c6ab2940fb0ad4a15026bf |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-05 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-06026 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B59-001 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-13 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-062 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C11C3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J75-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B59-00 |
filingDate |
2005-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b0f9b3ccb8afd262c8bcac8472d204e2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6a8e333dc16df7a83ba3db6e05a99e2e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d250246d53a8ecf2246ffc4fef2a903f |
publicationDate |
2008-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2008206820-A1 |
titleOfInvention |
Labeling Methods with Oxygen Isotopes |
abstract |
The present invention provides methods for labeling One or two oxygen atom(s) in a carboxyl group of a carboxyl-containing compound with an oxygen isotope selected from oxygen-17 ( 17 O) or oxygen-18 ( 18 O). The methods of the present invention are characterized in that an activated ester of the carboxyl-containing compound (carboxylic acid) is reacted with H 2 17 O or H 2 18 O in the presence of an activator. In the methods of the present invention, the reaction between the activated ester of a carboxylic acid and H 2 17 O or H 2 18 O can be allowed to proceed without including drastic conditions such as strongly acidic conditions or alkaline hydrolysis because an activator is used. |
priorityDate |
2004-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |