http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008176758-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6b2787fb8ac35a9508a61655fbcf73db http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e43d0655501a09fabc0769b5a1c20c6d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d74f627998af2484f02aa9e73331b9fc |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6827 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B40-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B30-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B30-04 |
| filingDate | 2007-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_36378313f5269cc1db2b79fe64d0dbb0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_61311186ef45e3300d9c57f3263c746d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f1854f639b88b3f70a9d26ab1c5f87d |
| publicationDate | 2008-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2008176758-A1 |
| titleOfInvention | Method for the analysis of the methylation status of a nucleic acid |
| abstract | The invention relates to a method for the analysis of the methylation status of a nucleic acid. According to the invention, the method comprises following steps: (a) treating the nucleic acid with a chemical reagent or an enzyme containing solution, whereby the base pairing behavior of methylated cytosine bases and/or unmethylated cytosine bases of the nucleic acid are altered such that methylated cytosine bases become distinguishable from unmethylated cytosine bases, (b) hybridizing to the treated nucleic acid an at least one oligonucleotide, (c) ligating the at least one oligonucleotide to itself to form a circular DNA molecule if a particular methylation status is present in the nucleic acid, and (d) amplifying the DNA molecule formed to detect the methylation status of the nucleic acid. |
| priorityDate | 2006-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 254.