| abstract |
The present invention relates to the fields of stably encapsulating oral care, skin care, scented, flavoring agents for cued release, and therapeutic agents for extended and sustained release. The invention relates to the stable microencapsulation of these agents for incorporation into dentifrices, topical ointments, microwavable food products, dryer sheets and chewing gums to be released during brushing, applying, heating, tumbling, and masticating respectively. Additionally, the invention encompasses extended and sustained release formulations that achieve reservoir-type delivery of therapeutic agents. The invention discloses methods for manufacturing and post-processing populations of chemically cross-linked elastomeric microcapsules allowing for the incorporation of encapsulated agents into a wide range of formulations without significantly altering their physio-chemical properties while providing for the cued delivery of the encapsulated agent upon the reception of a single or multiple mechanical or thermo-mechanical cues, or extended delivery via diffusion. |