| abstract |
Compounds of the general formula (I) in which R is heterocyclyl which is bonded via a carbon atom and is mono- or polysubstituted by C 1-6 -alkyl, trifluoromethyl, nitro, amino, C 1-6 -alkylamino, di-C 1-6 -alkylamino, C 2-6 -alkenyl, C 2-6 -alkynyl, C 1-6 -alkoxy, C 1-6 -alkylcarbonyloxy, C 0-6 -alkylcarbonylamino, C 1-6 -alkoxycarbonylamino, hydroxyl, halogen, oxide, cyano, optionally N-mono- or N,N-di-C 1-8 -alkylated carbamoyl, optionally esterified carboxyl or C 1-6 -alkylenedioxy, or is substituted by oxo and mono- or polysubstituted by C 1-6 -alkyl, trifluoromethyl, nitro, amino, C 1-6 -alkylamino, di-C 1-6 -alkylamino, C2-6-alkenyl, C 2-6 -alkynyl, C 1-6 -alkoxy, C 1-6 -alkylcarbonyloxy, C 0-6 -alkylcarbonylamino, C 1-6 -alkoxycarbonylamino, hydroxyl, halogen, oxide, cyano, optionally N-mono- or N,N-di-C 1-8 -alkylated carbamoyl, optionally esterified carboxyl or C 1-6 -alkylenedioxy, and salts, especially pharmaceutically usable salts have renin-inhibiting properties and can be used as medicaments. |