| abstract |
Disclosed is a method for inhibiting the propagation of an undesired cell population, the method comprising introducing into a cell an antagonist of SGT, or of a functional variant thereof, said antagonist depleting SGT, a functional variant thereof, in a cell of said cell population, and verifying the reduced proliferation and/or cell death in SGT depleted cell populations; disclosed is further the use of a SGT antagonist for the manufacture of a medicament for the treatment of diseases which are caused by the propagation of an undesired cell population. |