http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008146562-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_88dbd76310b7976c24992fab5ecfb075 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N43-84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N43-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N43-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N43-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N43-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N43-84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-517 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-00 |
| filingDate | 2007-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a43d0ae5f74804a797866e8de6a3230d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_33d2da12d22ffad1a917c683a6b82d8a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f919cbbbc8d9df50e61e501975389493 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fc589d145587e92670ea8a8999036082 |
| publicationDate | 2008-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2008146562-A1 |
| titleOfInvention | Halogenated quinazolinyl nitrofurans as antibacterial agents |
| abstract | The present invention includes novel compounds of the formula n n n n n n n n n n wherein: X is absent, or trans or cis CHCH; R 1 is (C 1 -C 10 )alkyl unsubstituted or substituted by one to three hydroxy, (C 2 -C 10 )alkenyl unsubstituted or substituted by one to three hydroxy, (C 2 -C 10 )alkynyl unsubstituted or substituted by one to three hydroxy, or aryl unsubstituted or substituted by one to three hydroxy; R 2 is hydrogen, alkyl or aryl, wherein R 1 and R 2 when taken together form a (C 2 -C 10 )cycloalkyl unsubstituted or substituted by one to three hydroxy; and R 3 and R 4 are, independently of each other, H, halogen, or n n n n n n n n n n wherein: P and R are each independently selected from CH 2 , CH 2 CH 2 and CH 2 CHT, wherein T is alkyl; Q is O, S, NH or NCH 3 ; and Y is absent or —CH 2 CH 2 ) n O—, and n=1 or 2; with the proviso that at least one of R 3 and R 4 is halogen, and that when R 4 is halogen, R 3 is hydrogen and Y is absent, neither R 1 nor R 2 are alkyl; or pharmaceutically acceptable salts thereof. n The invention also includes pharmaceutically acceptable formulations of said compounds which exhibit antibiotic activity against a wide spectrum of microorganisms including organisms which are resistant to multiple antibiotic families and are useful as antibacterial agents for treatment or prophylaxis of bacterial infections, or their use as antiseptics, agents for sterilization or disinfection. |
| priorityDate | 2003-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1373.