| abstract |
The present invention provides a pharmaceutical composition comprising a pharmaceutically acceptable excipient and a compound of the formula: n n n n n n n n n n wherein R 1 , R 2 , R 3 , R 5 , R 6 and R 8 are each independently a member selected from the group consisting of H, C 1-6 alkyl and OH; R 4 , R 7 and R 9 are each independently selected from the group consisting of C 1-6 alkoxy and OH; R 10 is a member selected from the group consisting of H, —OH, —OP(O)Me 2 , n n n n n n n n n n —O—(CH 2 ) n —OH and —O—(CH 2 ) m —O—(CH 2 ) o — CH 3 , wherein subscripts n and m are each independently from 2 to 8 and subscript o is from 1 to 6; each of L 1 and L 4 are independently selected from the group consisting of: n n n n n n n n n n each of L 2 and L 3 are independently selected from the group consisting of: n n n n n n n n n n salts, hydrates, isomers, metabolites and prodrugs thereof. |