Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_50bdeaf21406e51e60c050c7a42808fc http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a9c3c3ee0550e04c81e0a82f8adcff41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a1341e324e9432ed39e6d0571a1a48d3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2501a956339296ec65c11f27156b8c99 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-20034 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-20022 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-20023 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5258 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-12 |
filingDate |
2007-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3cf86abba842af8c04956b2dfe1d33e3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_04a5cb4b4a3392b7ef0bd6c2835e1050 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d9089abfe8b9718cbade4fa8b3ce302 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b371c97ac3a8a9fa45d6f448549ce83 |
publicationDate |
2008-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2008138361-A1 |
titleOfInvention |
Optimized expression of HPV 45 L1 in yeast |
abstract |
Synthetic DNA molecules encoding the HPV45 L1 protein are provided. Specifically, the present invention provides polynucleotides encoding HPV45 L1 protein, wherein said polynucleotides have been codon-optimized for high level expression in a yeast cell. The synthetic molecules may be used to produce HPV45 virus-like particles (VLPs), and to produce vaccines and pharmaceutical compositions comprising the HPV45 VLPs. The vaccines of the present invention provide effective immunoprophylaxis against papillomavirus infection through neutralizing antibody and cell-mediated immunity. |
priorityDate |
2003-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |