| abstract |
This invention relates to isophthalonitrile derivatives of formula (I) n n n n n n n n n n or pharmaceutically acceptable salts, solvates or derivative thereof, wherein R 1 to R 3 are defined in the description, and to processes for the preparation thereof, intermediates used in their preparation of, compositions containing them and the uses of such derivatives. n The compounds of the present invention bind to the enzyme reverse transcriptase and are modulators, especially inhibitors thereof. |