| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3fcb093a174d5182b5854b704cb09354 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-241
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 |
| filingDate |
2007-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_673dfd08cd9103e6dd5403e2a199738c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1cbb0640534a5b61c931ad3fdbb7d2e3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f5032ba6b488104c8965d8ec412ba253
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bff15e4cf481c5afe03fd4045be16b0c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b3a92b2a1aff5b1d0a74d9ff4413aa3c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a92ea67048e752e5c98d5a87f785b154 |
| publicationDate |
2008-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2008131432-A1 |
| titleOfInvention |
Method of treating the chemotoxic effects of chemotherapeutic drugs on brain tissue |
| abstract |
This invention is related to a novel method of treating the chemotoxic effects on the central nervous system of chemotherapeutic drugs, namely Adriamycin, by administering a therapeutically effective amount of anti-Tumor Necrosis Factor-α antibody to a patient to alleviate the symptoms of the effects. The antibody operates to decrease the serum level of Tumor Necrosis Factor-α, prevents the p53 translocation to mitochondria and prevents the decline in mitochondrial respiration of brain tissues and thereby relieves the symptoms of somnolence caused by chemotherapeutic drugs. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2013519718-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016193928-A |
| priorityDate |
2005-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |