http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008124246-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3e1018b924ad1e238642eaad9d2172a7 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T156-10 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6452 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 |
filingDate | 2006-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_33ab70dfef9b1cfd5d9224fdd8ea333f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_26566bbd23f305d4c0e91da7a550934f |
publicationDate | 2008-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2008124246-A1 |
titleOfInvention | Microdevice for a Fluorescence-based Assay, and a Method for Making the Microdevice |
abstract | Glass as a substrate for fluorescence-based assays is expensive. Disclosed is a poly(cyclic olefin) alternative to glass that is of comparable sensitivity. More specifically, disclosed is a method of making a microdevice for the immobilization of biomolecules for the purpose of carrying out a fluorescence-based assay, said method comprising providing a substrate comprising a poly(cyclic olefin); protecting the substrate from ultraviolet (UV) light; and subjecting a surface of said UV-protected substrate to ozone oxidation to activate said surface; wherein a content of intrinsic fluorophores on the surface of the substrate remains substantially unchanged after the ozone oxidation. Also disclosed is a microdevice for the immobilization of biomolecules for the purpose of carrying out a fluorescence-based assay, said microdevice comprising a body comprising a poly(cyclic olefin), said body having an ozone-activated surface substantially free of intrinsic fluorophores; wherein said activated surface is substantially free of intrinsic fluorescence during a fluorescence-based assay of said biomolecules bound to said activated surface. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009081797-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012302427-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8969648-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8926881-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9211176-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9492952-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10278701-B2 |
priorityDate | 2006-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 129.