| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_33b011e77b33662b8bf1f2ff2de7b661 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-2462 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 |
| filingDate |
2006-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7548424aa0545259daa9bceff958bd0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_221c03971c08ff4541a03e64766f1dcb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b068a66eac2f2ebfcbbdd713575aecd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fdcc34296f5662146fc3a5ae3efc5c02 |
| publicationDate |
2008-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2008118489-A1 |
| titleOfInvention |
Charge-Modified Lysozyme Antimicrobial Compositions, Surfactants, and Methods for Infections and Cystic Fibrosis |
| abstract |
The invention comprises charge modified antimicrobials, including charge modified lysozymes, as well as compositions and methods for potentiating antimicrobial activity by modifying a net charge level of the antimicrobial. Also provided is a method of treating microbial infections, including infections associated with cystic fibrosis, comprising administering or co-administering a compound of the invention. The invention provides compositions and methods of potentiating antibiotic treatment by administration of an at least partially cationic or positively-charged surfactant composition. Cationic lipid compositions including DOTAP:DOPE formulations are disclosed. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9074201-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9950041-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010083504-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010083504-A3 |
| priorityDate |
2005-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |