http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008114008-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ba1303ccef7c3a8ed8a6de0cf7459278 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-94 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C255-61 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-94 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-517 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C255-61 |
| filingDate | 2006-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_59bbaa8ce201f6ee16c3647eb180f52c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f411c4d56bf64fe19a461b4225a65a0c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_804fa2a558795e3e3e8953f5afe0fa88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e8018518f1d023b1a9b19431f5641366 |
| publicationDate | 2008-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2008114008-A1 |
| titleOfInvention | Quinazoline Derivatives as Antiviral Agents |
| abstract | Compounds of formula (I) are found to be active in inhibiting replication of flaviviridac Formula (I) wherein: X represents a direct bond or a moiety -L-NR—, wherein R is hydrogen or C 1 -C 4 alkyl, and L represents a C 1 -C 4 alkylene, C 6 -C 10 aryl or 5- to 10-membered heteroaryl moiety; either R 1 and R 2 , together with the N atom to which they are attached, form a 5- to 10-membered heterocyclyl group or a 5- to 10-membered heteroaryl group, or R 1 represents hydrogen, C 6 -C 10 aryl, C 1 -C 4 alkyl or C 1 -C 4 hydroxyalkyl and R 2 represents C 6 -C 10 aryl, C 1 -C 4 alkyl or C 1 -C 4 hydroxyalkyl; and R 3 represents a C 6 -C 10 aryl, C 3 -C 6 carbocyclyl, 5- to 10-membered heteroaryl or 5- to 10-membered heterocyclyl moiety, said aryl, carbocyclyl, heteroaryl and heterocyclyl groups being unsubstituted or substituted by 1, 2 or 3 substituents selected from halogen, C 1 -C 4 alkyl, C 1 -C 4 alkoxy, C 1 -C 4 haloalkyl, C 1 -C 4 haloalkoxy, hydroxy, thiol, —NH 2 , C 1 -C 4 hydroxyalkyl, C 1 -C 4 thioalkyl and C 1 -C 4 aminoalkyl substituents. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008267914-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010158863-A1 |
| priorityDate | 2005-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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