abstract |
The present invention is directed to novel bicyclic pyrimidine compounds of Formula (I) or a form or composition thereof n n nas inhibitors of ATP-protein kinase interactions, wherein substituents on each side of the iminomethyl double bond in Formula (I) may be in the E or Z configuration; and wherein R 1 , R 2 , R 3 and R 4 are as defined herein. |