abstract |
The invention relates to an immediate release tablet capable of being chewed or disintegrated in the oral cavity, which comprises a plurality of particles in a matrix. The particles contain an active ingredient, such as ibuprofen, and a first water soluble acid having a solubility greater than about 10 g/100 mL water at 20° C.; and the matrix contains a second water soluble acid having a solubility less than about 5 g/100 mL water at 20° C. |