| abstract |
The present invention provides compounds of the formula: n n nand pharmaceutically acceptable isomers, salts, hydrates, solvates, and prodrug derivatives thereof, wherein R 1 , R 6 , R 7 , R 8 , Pg, and n are those defined herein. The present invention also provides pharmaceutical compositions comprising the same and methods for using the same. In particular, compounds of Formula I are useful in modulating TGF-β activity. |