| abstract |
The present invention provides an oral composition which is effective for the prevention or treatment of periodontal disease such as gingivitis, periodontitis and alveolar pyorrhea. According to the present invention, there can be provided an oral composition such as a dentifrice, a mouthwash or a gingival massage cream which is effective for the prevention or treatment of periodontal disease, said composition comprising an N-acyl derivative of hydroxyproline such as an N-acetyl derivative, an N-propionyl derivative, an N-butyryl derivative or an N-isobutyryl derivative, or a salt thereof. |