| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a36c20329430ad62d297a93a6a8aefa4 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-13
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-204998
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-497 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0455 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-04 |
| filingDate |
2007-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b293e454e20ed691908fe5a36d247ae
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_513d63267e8a6acbc216a525d6a888d8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb48bd939028a33564a7d383e21821b6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f04fd39913118a769a98e5c7d86fadf9 |
| publicationDate |
2008-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2008085240-A1 |
| titleOfInvention |
Method and composition to evaluate cytochrome p450 2c19 isoenzyme activity using a breath test |
| abstract |
The present invention relates, generally to a method of determining and assessing cytochrome P450 2C19-related (CYP2Cl9) metabolic capacity in an individual mammalian subject via a breath assay, by determining the relative amount of 13 CO 2 exhaled by the subject upon intravenous or oral administration of a 13 C-labeled CYP2C19 substrate compound. The present invention is useful as a non-invasive, in vivo assay for evaluating CYP2C19 enzyme activity in a subject using the metabolite 13 CO 2 in expired breath, to phenotype individual subjects and to determine the selection, optimal dosage and timing of drug administration. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8073632-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8073633-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8084210-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011060532-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8315815-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8321151-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011045481-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010169022-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010169023-A1 |
| priorityDate |
2006-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |