| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1cc08712d5a2d6bffa4bf7fe13d8cd61
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4358495b370b6274495bf5ad49bf4e5b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9b8f514ebf67600a71f9eea146779a10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_faa2d6cde9cea0b535f9343eb87f6bc3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c0766def518b742bc5e712ee601f536f |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-38 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08L101-02 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L37-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L35-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L33-02 |
| filingDate |
2007-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8298759b4c05e8ea1134289aac6bd3fd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2eea72c6e7f9561a5ac58af62cac3580
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_06f4a55e12e9966fe1b75a37a6b50b9b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d6530cf239b18dd13786f3a5a9757f2e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d0d369cd46f8e435c1195ac44bbbaca1 |
| publicationDate |
2008-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2008076852-A1 |
| titleOfInvention |
Method to repair a damaged intervertebral disc through the use of a bioadhesive, thermogelling hydrogel |
| abstract |
The present invention is directed to a bioadhesive thermogelling hydrogel composition for repairing and/or augmenting an intervertebral disc. The bioadhesive thermogelling hydrogel composition can be cross linked with the surrounding tissue so as to potentially serve as a nucleus pulposus replacement or augmentation along with serving to repair annular tears or fissure. The bioadhesive thermogelling hydrogel composition may include three main components: a thermal responsive polymer, an amine-containing polymer and a crosslinking component. All three components can be modified and combined in numerous ways to serve the need of the system as long as the amine-containing component is kept separate from the crosslinking component until the components are injected. The incorporation of a two-part crosslinking thermal responsive hydrogel permits smaller amounts of the crosslinking component to be used and enables the crosslinking dialdehyde to be delivered locally into the tissue that will react with the hydrogel. This helps prevent damage to tissues away from the hydrogel. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022015723-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010286786-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103170008-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017176973-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11179493-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015267196-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8366778-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013086523-A3 |
| priorityDate |
2006-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |