abstract |
Disclosed are compounds of the formula n n nwherein Z 1 is βCH 2 β or βC(O)β, R 4 and R 5 are carbon chains (and optionally, together can form a C 2 bridge), u and v are independently an integer of 0-3 such that there sum is from 3 to 5, and R 2 is heteroaryl, and R 1 and R 3 are as defined herein. Also disclosed are methods of treating pain, and methods of inhibiting the absorption of cholesterol using a compound of formula I. |