http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008064742-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e6626da7dfbbc4c180cbd2cdf64ab773 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_433877e201987ce69af6737cbc2548ca |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-94 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-35 |
| filingDate | 2005-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_44a84154dd348f2cf237d70e811e34a4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c176747a238cda6ae0c889c69bed405a |
| publicationDate | 2008-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2008064742-A1 |
| titleOfInvention | Substituted Benzopyrans as Selective Estrogen Receptor-Beta Agonists |
| abstract | The present invention relates to novel benzopyran ER-β agonist compounds, pharmaceutical compositions thereof, and use of these compounds to treat a ER-β mediated disease such as nocturia, obstructive uropathy, benign prostatic hypertrophy, obesity, dementia, hypertension, incontinence, colon cancer, prostate cancer, infertility, depression, leukemia, inflammatory, bowel disease, and arthritis. Formula (I), wherein G is —O—, —S(O)—, —CF 2 —, —C(O)—, —CR 1 H— or —CR 2 (OH)—; R is halo, (C 1 -C 4 )alkyl or R 2 —(CH 2 ) m —; R 1 is F, hydroxyl, cyano, trifluoromethyl, (C 1 -C 4 )alkyl, (C 2 -C 4 )alkenyl, (C 2 -C 4 )alkynyl, (C 1 -C 4 )alkoxy, (C 1 -C 4 )alkycarbonyloxy or benzyl; R 2 is trifluoromethyl or (C 1 -C 4 )alkyl; R 3 is cyano, hydroxyl, (C 2 -C 4 )alkenyl, (C 1 -C 4 )alkoxy or (C 1 -C 4 )alkoxycarbonyl; n is 0, 1 or 2; and m is 0, 1 or 2; and pharmaceutically acceptable salts thereof. |
| priorityDate | 2004-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 911.