| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b9ca0632596f3342a71f604d9152b9e1 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6816 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate |
2005-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb59a49a779e174950f8617a6527d12c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d37672e9aa71fcceb1bb450f1e5d4821 |
| publicationDate |
2008-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2008064033-A1 |
| titleOfInvention |
Molecular Beacons |
| abstract |
The invention relates to a molecular beacon in the form of a hairpin oligonucleotide or oligonucleotide analogue comprising a first nucleotide sequence containing two or more aromatic or heteroaromatic ring systems P able to form an excimer or exciplex; a second sequence (the loop) consisting of an oligonucleotide probe able to hybridise with a target polynucleotide; and a third sequence containing one or more aromatic or heteroaromatic ring systems X, wherein at least one aromatic ring system X interacts with two aromatic ring systems P of the first sequence inhibiting excimer or exciplex formation. The invention further relates to a method for detecting the presence of a target polynucleotide using such a molecular beacon, and to a kit comprising a molecular beacon of the invention for use in this method. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019022520-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10400276-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11066700-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101899372-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101899371-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11091802-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102361993-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9234232-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20190011707-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011207131-A1 |
| priorityDate |
2004-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |