| abstract |
A modified release pharmaceutical composition comprising, as active ingredient, a compound of formula (I), wherein R 1 represents C 1-2 alkyl substituted by one or more fluoro substituents; R 2 represents hydrogen, hydroxy, methoxy or ethoxy, and n represents 0, 1 or 2; or a pharmaceutically acceptable salt thereof; and a pharmaceutically acceptable diluent or carrier; provided that the formulation may only contain iota-carageenan and a neutral gelling polymer when the compound of formula (I) is in the form of a salt; such formulations being of use for the treatment of a cardiovascular disorder. |