http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008045523-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aff6633139e8f79659a0587cc38a6c07 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D319-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D319-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D319-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-341 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-357 |
| filingDate | 2005-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d50dae90a54a31892d4edac0a7b89edb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5393c7bae3ecd559cdc2bd593353e07e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_961c423e50be4a9c2e97d88065cbb08e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_360adb800dea8eced0164c0a31680305 |
| publicationDate | 2008-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2008045523-A1 |
| titleOfInvention | Synthesis of Polyoxygenated Nitrogen Systems, Comprising Reactions Between Enamines of 1,3-Dioxan-5-Ones and Nitroolefins |
| abstract | The invention relates to the synthesis of polyoxygenated nitrogen systems, comprising reactions between enamines of 1,3-dioxan-5-ones and nitroolefins. More specifically, the invention relates to the reaction between enamines having formula II which are derived from 1,3-dioxan-5-ones I and nitroolefins having formula III. In this way, novel polyoxygenated nitrogen systems are generated having formula IV and V, which, as they are or following simple transformations, constitute synthetic intermediates and/or analogues of different systems of proven biological/pharmacological interest, such as certain antibiotics, or tetrodotoxin, pancratistatin or the analogues thereof. The aforementioned reactions involve the use of enamines II in Michael-type addition reactions and in direct annealing processes with double acceptor systems at relative positions 1, 3. Said N acceptors include nitroolefins III, wherein R═CHO (alphanitroenals). The invention also relates to the preparation thereof, which is based on the oxidation of the corresponding precursor alcohols VII, and the use of same in annealing processes. |
| priorityDate | 2004-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 262.