abstract |
The present invention relates to a molecular spacer arm, to a process for attachment of a molecular unit to a solid support, and also to the use of this spacer arm on analytical chips comprising molecules or biomolecules. The spacer arm has the formula (I): n n nin which X 0 , X 4 ═C, O, S, Se, N, P, As; X 1-3 ═C, O, N, S, Se, P, As, or C 1-6 aryl or heteroaryl; Z 1-2 ═C—R, Si—R, N, P and As, where R═C 1-6 alkyl; R 1-3 ═H, or C 1-6 alkyl, aryl or heteroaryl; [Gp]=protective group for >N; n, m and p=integers ≧1; [Sup]=H or a silanized solid support; and [mo]=H or a molecular unit intended to be covalently attached to said silanized solid support by means of said spacer arm. |