Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_143f475d8bc81e16c0db654c62bb7faf http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8ba8bfd18d975aaeb9ec7cd047c96390 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_88c49594cd4c58693cc9654f75201cb9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_48b865e0b69f8985d16243c2d853ba41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_49777b3455faf88359f3c7c89e368a94 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-136 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-67 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-775 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6897 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7068 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-775 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-79 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-67 |
filingDate |
2007-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ddffb53bb8294b75b163da03debd4254 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e352a98e0f83101afac3fa05250937cb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_015195147cf47f2b2136489e842dd062 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1ce7dda2ea515ab06daafaf822f95ba2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_352e8fedfbf47dd933d6a3b89d0f13d3 |
publicationDate |
2008-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2008009060-A1 |
titleOfInvention |
Methods of discovering chemicals capable of functioning as gene expression modulators |
abstract |
The present invention provides a method of transcriptionally modulating the expression of a gene-of-interest. The method comprises contacting a cell which is capable of expressing the gene with an amount of a molecule effective to transcriptionally modulate expression of the gene and thereby affect the level of the protein encoded by the gene which is expressed by the cell. Molecules useful in the practice of the invention are characterized as follows (a) do not naturally occur in the cell, (b) bind to DNA or RNA or bind to a protein through a domain of such protein which is not a ligand binding domain of a receptor which naturally occurs in the cell. Additionally, this invention provides a method for determining whether a molecule known to be a modulator of protein biosynthesis is capable of transcriptionally modulating expression of a gene-of-interest. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10301620-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2014031412-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11046956-B2 |
priorityDate |
1989-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |