| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d8eaca416b4379f6f962ed7022a5f72a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_62588aa0b9e55bf21127388937bd3fd9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6fc7c0f72a30eba554aad8aecac9ff53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5b09069286651a4e4b58add7072a4b78
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a72145052d195009b7c83ffd3a92872a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-916
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-9125
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-02 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-574
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y207-07049
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1241 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 |
| filingDate |
2005-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_85bcb477f8ca4e6242a02c9987a008fa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab3b9335ff4700ea567b181a4b23c089
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ab7f4e89e73d0e6f52e61104a63c576
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94d9119951084eb9b5b542996b7fd4c1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4faf3d872b4b7fdc48241fbc4f7899e7 |
| publicationDate |
2008-01-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2008004355-A1 |
| titleOfInvention |
Method for Inhibiting Telomerase Activity and an Agent for Inhibiting the Same |
| abstract |
A method is described for enhancing degradation of telomerase. This method includes inhibiting the binding of TERT (telomerase catalytic subunit) to USP21, the binding of NEDD8-conjugated TERT to USP21, or the NEDD8 deconjugation by USP21 from NEDD8-conjugated TERT. A method of inhibiting telomerase activity is also described. The method includes utilizing the method of enhancing the degradation. A method of identifying a compound that inhibits the binding or the NEDD8 deconjugation is further described. An agent for inhibiting telomerase activity is described. An agent for preventing and/or treating diseases attributable to the enhanced telomerase activity is described and includes an inhibitory agent. Also, a method of preventing and/or treating diseases is described and includes using the inhibition method or the inhibitory agent. Further, a reagent kit is described. |
| priorityDate |
2004-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |