| abstract |
A composition for use in the delivery of a first active agent and a second active agent, the first active agent being sequentially deliverable after the second active agent, the composition comprising hollow mineral microtubules, each of the hollow mineral microtubules having a length, and opposing ends; and including a cylindrical wall, and a hollow lumen; and a central region, an intermediate region, and an outer region along the length; and within the microtubules, the first active agent disposed within the lumen in the central region of the microtubules, and the second active agent disposed within the lumen in the intermediate region of the microtubules. The composition may also be provided for the delivery of three or more active agents in sequence. There is further provided methods for making the compositions of the present invention. |