Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9b4f16ad70ddfeb0b838c113aaae408a |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2602-10 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C209-84 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-26 |
filingDate |
2006-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc03d5abe948ae29a8c1bfb6bc828ee1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9469c17f097ac3c6c3251618bce01fd5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5040363bf76abada024062d25cec407 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e17fa7eabd2826686efd4a96c01ef35c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a58041c1d4c84469304b71946babb50 |
publicationDate |
2007-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2007282129-A1 |
titleOfInvention |
Novel processes for preparing sertraline hydrochloride crystalline forms |
abstract |
The present invention discloses novel and improved processes for preparation of sertraline hydrochloride crystalline form II. Thus, for example, sertraline free base is dissolved in isoamyl alcohol at 25-30° C., pH of the mass is adjusted to 2.0 with conc. hydrochloric acid (36%) at 25-30° C. and then stirred for 14 hours at 25-30° C. Filtered the solid and dried at 65° C. for 4 hours to give sertraline hydrochloride crystalline form II. The present invention also provides a novel process for preparation of sertraline hydrochloride crystalline form I. |
priorityDate |
2006-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |