http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007270471-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_27a71ddaaa2f5a8c228fc6cb3f3b3098 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-10 |
filingDate | 2005-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_510288175fde48dd2e59a750a1c4f7c4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f905044aa28190e796db502026e96f6e |
publicationDate | 2007-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2007270471-A1 |
titleOfInvention | Compounds Which Potentiate Glutamate Receptor and Uses Thereof in Medicine |
abstract | This case discloses compounds of formula (I) n n nwherein R 1 is C 1-6 alkyl, haloC 1-6 alkyl, C 2-6 alkenyl, amino, monoC 1-4 alkylamino or diC 1-4 alkylamino; B is —N(R 4 )— or —O—; A and D, which may be the same or different, are —C(R 5 ) 2 —; each R 2 , which may be the same or different, is C 1-6 alkyl, halogen, haloC 1-6 alkyl, C 1-4 alkoxy, haloC 1-4 alkoxy, cyano, nitro or amino; n is 0, 1 or 2; R 3 is C 1-6 alkyl, haloC 1-6 alkyl, C 1-4 alkoxy, haloC 1-4 alkoxy, cyano, nitro, amino, —(CH 2 ) p NR 3a SO 2 R 3b , —(CH 2 ) p NR 3a (C═O)R 3b , —(CH 2 ) p NR 3a (C═O)N(R 3c ) 2 , —(CH 2 ) p (C═O)R 3d , —(CH 2 ) p SO 2 R 3e , phenyl or heterocyclyl, wherein when R 3 is phenyl or heterocyclyl, it is optionally substituted by one or more groups independently selected from: C 1-6 alkyl, halogen, C 1-6 alkyl, haloC 1-6 alkyl, C 1-4 alkoxy, haloC 1-4 alkoxy, cyano, nitro, amino, —(CH 2 ) p NR 3a SO 2 R 3b , —(CH 2 ) p NR 3a (C═O)R 3b , —(CH 2 ) p NR 3a (C═O)N(R 3c ) 2 , —(CH 2 ) p (C═O)R 3d and —(CH 2 ) p SO 2 R 3e ; where R 3a and each R 3c , which may be the same or different, is hydrogen or C 1-6 alkyl; R 3b and R 3e are C 1-6 alkyl or haloC 1-6 alkyl; R 3d is C 1-6 alkyl, C 1-4 alkoxy or haloC 1-6 alkyl; or R 3a and R 3b , or R 3a and R 3c , together with the interconnecting atoms, may form a 5- or 6-membered ring; and p is 0, 1, or 2; R 4 is carbocyclyl or carbocyclylC 1-4 alkyl, wherein the carbocyclyl group of either is optionally substituted by one or more groups independently selected from C 1-6 alkyl and halogen; or R 4 is hydrogen, C 1-6 alkyl, haloC 1-6 alkyl, C 1-6 alkylcarbonyl, C 1-6 alkylsulfonyl or C 1-6 alkylaminocarbonyl; each R 5 , which may be the same or different, is hydrogen, C 1-6 alkyl or halogen; and R 6 is hydrogen or fluorine. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009070533-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7790758-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008167351-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11098029-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11034669-B2 |
priorityDate | 2004-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
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