| abstract |
Methods and kits for delivering pharmaceutical agents to the sinuses, sinus ostia, Eustachian tube, and pharynx are presented. A needle tip is translated through the mucosal tissue layer to a sub-epithelial or peri-luminal orientation and pharmaceutical agents are delivered into the sub-epithelial or peri-luminal tissue. Drugs distribute from the site of infusion to treat conditions including sinusitis and allergic rhinitis, among others. |