abstract |
Compounds are provided of the following structure are HMG CoA reductase inhibitors and thus are active in inhibiting cholesterol biosynthesis, modulating blood serum lipids, for example, lowering LDL cholesterol and/or increasing HDL cholesterol, and treating hyperlipidemia and dyslipidemia, hypercholesterolemia, hypertriglyceridemia and atherosclerosis n n n n n n n n n n wherein A is chosen from n n n n n n n n n n n n B is chosen from n n n n n n n n n n n n n n n n n n n n n wherein the variables R 1 to R 7 , m, n, n n n n n n n n n n are as defined herein. n A method for treating the above diseases employing the above compounds is also provided. |