Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4a5e258344b1f107584e79fa7d4983c2 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2866 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5026 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5073 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5078 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5084 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-24 |
filingDate |
2007-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_679ea65929bdbeb9e47bc0a0159644f5 |
publicationDate |
2007-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2007243250-A1 |
titleOfInvention |
Oral Dosage Formulations and Methods of Preparing the Same |
abstract |
A method of optimizing a dissolution profile for a selected active agent dosage form, comprises combining a first amount of a first ensemble of pulsed-release pellets having a first dissolution profile with a first T50 and a second amount of a second ensemble of pulsed-release pellets having a second dissolution profile with a second T50 to produce a combination ensemble of pellets having a combination dissolution profile of a combination slope, wherein the combination slope corresponds to a single phase release, and wherein the combination slope is greater than 10% lower than the slope of the first dissolution profile and greater than 10% lower than the slope of the second dissolution profile, and wherein the first ensemble of pellets and the second ensemble of pellets comprise a core having disposed thereon a core composition layer, the core composition layer comprising the active agent, and a pulsed-release coating disposed on the core composition layer. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8623418-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8685443-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8685444-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2022031622-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114425046-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114425046-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010310608-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8846104-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8877247-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008233156-A1 |
priorityDate |
2006-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |