http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007243245-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4a5e258344b1f107584e79fa7d4983c2 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2081 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5078 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5026 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-62 |
filingDate | 2007-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_679ea65929bdbeb9e47bc0a0159644f5 |
publicationDate | 2007-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2007243245-A1 |
titleOfInvention | Oral Dosage Formulations, Methods of Preparing the Same, and Methods of Reducing Food Effects on Drug Release |
abstract | A multi-particulate oral dosage form, comprising a plurality of pellets, the pellets comprising a core having disposed thereon a core composition layer, the core composition layer comprising an active agent, and a sustained-release coating disposed on the core composition layer, wherein the sustained-release coating comprises a first polymer comprising a copolymer of acrylic and methacrylic esters comprising quaternary ammonium groups and having a ratio of quaternary ammonium groups to neutral meth(acrylic) esters of 1:40 and optionally a second polymer comprising a copolymer of acrylic and methacrylic esters comprising quaternary ammonium groups and having a ratio of quaternary ammonium groups to neutral meth(acrylic) esters of 1:20, wherein the ratio of the first polymer to the second polymer is about 50:50 to about 100:0, and wherein the first and second polymer comprise about 20 wt % to about 90 wt % of the total weight of the sustained-release coating; and about 10 wt % to about 50 wt % of colloidal silicon dioxide, based on the total weight of the alcohol-soluble material in the sustained-release coating. Methods of making the dosage form and methods of reducing food effects by administering the dosage form to a human subject are also disclosed. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114425046-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114425046-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10485753-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8685443-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8685444-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010310608-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008233156-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11096887-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11052060-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11013707-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9730885-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8940729-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8846104-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8716337-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8877247-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8623418-B2 |
priorityDate | 2006-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 674.