| abstract |
An aldol reaction in an aqueous solution between an aldehyde represented by the following formula (I): n nR—CHO (I) n n(wherein R is a hydrocarbon group which may have an substituent), and a silicon enolate represented by the following formula (II): n n n (wherein R 1 and R 2 are a hydrogen atom or an aliphatic hydrocarbon group, at least one of them being an aliphatic hydrocarbon group; and n R 3 is a substituent selected from the group consisting of an aliphatic hydrocarbon group, an aromatic hydrocarbon group and a sulfur-containing substituent, wherein R 2 and R 3 may be combined with each other to form a ring) is performed so as to generate diastereoselectivity by using FeCl 3 , which is a low-cost Lewis acid, and a surfactant. |