| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_78941ed5a01bfbcd48376e1fdb485b19 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-142
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate |
2007-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6eca7385604e13eb6870499a13d8f0c9 |
| publicationDate |
2007-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2007218487-A1 |
| titleOfInvention |
Genetic markers for predicting disease and treatment outcome |
| abstract |
The present invention provides for a method for identifying patients that are suitably treated by a therapy, such as a therapy involving administration of a fluoropyrimidine drug and/or a platinum drug. The method includes determining the expression level of at least one gene selected from a phospholipase 2 (PLA2) gene, a thymidine phosphorylase (TP) gene, and a glutathione S-transferase P1 (GSTP-1) gene in suitable sample isolated from the patient. Overexpression of the gene or genes identifies the patient as not being suitable for the therapy. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010183593-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008286789-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7662553-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7807364-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010173922-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009181016-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7727724-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006115827-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102165315-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006094012-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8318426-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8435752-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011020333-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009114811-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007244083-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007207486-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2635525-C2 |
| priorityDate |
2006-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |