http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007218460-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_28e3113097dd6d28720572e47f2f2407 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5023 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6876 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
| filingDate | 2004-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_796b3902dd7c890fa71ff25ea18c03a4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e95b55c3257ebd122ecf4364785211f8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b83dd7c978585c312b51182c298eda4b |
| publicationDate | 2007-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2007218460-A1 |
| titleOfInvention | Method of Estimating Toxicity of Drug |
| abstract | The present invention provides a novel in vitro prediction system of a phospholipidosis inducing potential of a novel drug-caused phospholipidosis marker gene and a drug. Specifically, the invention provides a reagent for prediction of a phospholipidosis inducing potential of a compound containing a nucleic acid capable of detecting the expression of a gene having the same or substantially the same base sequence as the base sequence shown in SEQ ID NO:1, 3, 5, 7, 9, 11, 13, 15, 17, 19, 21 or 23. Furthermore, the invention provides a method for predicting a phospholipidosis inducing potential of a compound, which includes detecting the expression of two or more genes showing expression variation in correlation with phospholipidosis expression in a mammalian cell exposed to a test compound. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8313949-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009123377-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010267061-A1 |
| priorityDate | 2003-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1057.