abstract |
The present invention relates to a new use of a compound of the formula (I) n n wherein R 1 is NH 2 , piperazin-1-yl, 4-methylpiperazin-1-yl, 4-methyl-1,4-diazepan-1-yl or 4-ethylpiperazin-1-yl; R 2 is hydrogen, fluoro, CH 3 , CH 2 CH 3 , OCH 3 , CF 3 or OCF 3 ; R 3 is hydrogen, CH 3 or fluoro; as a free base or a pharmaceutically acceptable salt thereof, in the manufacture of a medicament for the prevention and/or treatment of bone-related disorders, osteoporosis and increasing bone formation, bone mineral density. The present invention further relates to a method of prevention and/or treatment of these disorders. |