Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5bc5292a07e34d16eb1d033a16d3aec3 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-87 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
filingDate |
2006-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c07c16b016efec2b1bc46fed9ab5767 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf530d4731ea1b2612da77aa060fc0e4 |
publicationDate |
2007-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2007207966-A1 |
titleOfInvention |
Polymeric carrier for delivery of small interfering RNA |
abstract |
A carrier for delivering small interfering RNA (siRNA) into cells includes a cholesterol residue covalently bonded to oligoarginine. Mixing the siRNA with the carrier produces a complex-containing composition. Contacting a cell with the complex-containing composition results in delivery of the siRNA into the cell. Delivery of an siRNA targeted to vascular endothelial growth factor is a treatment for cancer. Methods of making the carrier and complex are also disclosed. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9006193-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2013065942-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009105179-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2530169-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014051318-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9827331-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2368300-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101497668-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008026077-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015290340-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9713645-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9144546-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011143435-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014051318-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8003621-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9468687-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104870023-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011135138-A1 |
priorityDate |
2006-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |