Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_01ee453e6f32ec34406f4fd252d4bbc3 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10343 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10345 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2810-859 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6901 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-70 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-861 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00 |
filingDate |
2007-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_90f648a87d0a1677caffdab044739dd6 |
publicationDate |
2007-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2007202524-A1 |
titleOfInvention |
Targeted Vectors |
abstract |
This invention provides therapeutic and diagnostic agent delivery vehicles, including viral vectors, that are complexed to a targeting moiety by coordinate covalent linkages mediated by a transition metal ion. The complex is typically formed with a transition metal ion that is in a kinetically labile oxidation state; after the complex is formed, the oxidation state of the transition metal ion is changed to one that renders the complex kinetically stable. The use of a coordinate covalent linkage to attach the targeting moiety to the delivery vehicle provides advantages such as the ability to readily attach a different targeting moiety to a delivery vehicle without modifying the delivery vehicle itself. This flexibility is achieved without sacrificing stability of the complex. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10155930-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10300096-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11268073-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11130968-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010310554-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10538744-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011275093-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11077156-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010311145-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10731136-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11369650-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2017252443-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11401529-B2 |
priorityDate |
1999-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |