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publicationDate 2007-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2007184479-A1
titleOfInvention Method for hybridizing nucleic acids and hybridization apparatus
abstract A method for hybridizing a target nucleic acid and a probe nucleic acid that can specifically bind to the target nucleic acid and that is immobilized on a substrate includes a first reaction step of allowing the target nucleic acid contained in a sample solution to react with the probe nucleic acid, a recovery step of recovering the sample solution after the first reaction step, a heating step of heating the recovered sample solution to the denaturation temperature of the target nucleic acid or a higher temperature, and a second reaction step of allowing the target nucleic acid contained in the sample solution after the heating step to react with the probe nucleic acid.
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