Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_76c7637f038d75291ef90935a84f8ea6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b4be7cc937ec2c0f4aad489e62e0a53d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b832b0bafc0440235674626ffc8fc1dd |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2799-022 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2840-203 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4746 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
filingDate |
2005-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8169bbaa02d3f4e6e07fb0f7c9c3c760 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d160aa07eafec8e974360e9ffc590307 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d9789c3c7bc52900d290ea593bbb0066 |
publicationDate |
2007-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2007173443-A1 |
titleOfInvention |
C-Terminal P53 Palindromic Peptide That Induces Apoptosis Of Cells With Aberrant P53 And Uses Thereof |
abstract |
Disclosed are polypeptides comprising a first segment of continuous amino acids having the sequence AQAGKEPGGSRAHSSHLKSKKGQSTSRHKKLMFKTEGPDSD (SEQ ID NO. 1) covalently linked to a second segment of continuous amino acids having the sequence DSDPGETKFMLKKHRSTSQGKKSKLHSSHARSGGPEKGAQA (SEQ ID NO. 2), or at least two of each covalently linked to each ether. The polypeptides are shown to induce apoptosis of cancer cells that contain mutant p53 or over-expressed wild-type p53. |
priorityDate |
2004-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |