http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007172937-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_76ba102ea9c02b6633d64bf09c5b89a4 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1029 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-67 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y203-01054 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 |
filingDate | 2007-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bed849714316dfff28d678b9b1d18b1c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4841f3fcca59f7527560057319421f50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d4c9645f37666a1b669b0e772f889c1b |
publicationDate | 2007-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2007172937-A1 |
titleOfInvention | Recombinant cells that highly express chromosomally-integrated heterologous genes |
abstract | Recombinant host cells are obtained that comprise (A) a heterologous, polypeptide-encoding polynucleotide segment, stably integrated into a chromosome, which is under transcriptional control of an endogenous promoter and (B) a mutation that effects increased expression of the heterologous segment, resulting in enhanced production by the host cells of each polypeptide encoded by that segment, relative to production of each polypeptide by the host cells in the absence of the mutation. The increased expression thus achieved is retained in the absence of conditions that select for cells displaying such increased expression. When the integrated segment comprises, for example, ethanol-production genes from an efficient ethanol producer like Zymomonas mobilis , recombinant Escherichia coli and other enteric bacterial cells within the present invention are capable of converting a wide range of biomass-derived sugars efficiently to ethanol. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008090283-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009061501-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8715977-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009053793-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011137088-A1 |
priorityDate | 1988-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 492.