| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ae40a5adec69affe7d566d97d782c4f3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3f8fd487ae515a3870f6bdf33d42b38f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fc9a5c5998dc6fd21b1e96fab7cf820e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_770f5342d8e8630c45387f96b007ad2e |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-522
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-689
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-24 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-689
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06F19-00 |
| filingDate |
2004-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c49652e504a58b51a3aa594e7b3f5207
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e67f983f0ae6f0b4d2d3ee5a39d3681
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b48789373c9452b59c2e9dbccd584034
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5039767389bc37b806c1d1e42a89d519 |
| publicationDate |
2007-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2007160986-A1 |
| titleOfInvention |
Method for identification of novel virulence associated genes |
| abstract |
In a method of identifying novel virulence associated genetic information about a pathogenic microorganism including information about open reading frames (ORFs) having (a) assigned functions, (b) no assigned functions, (c) showing similarity with hypothetical proteins from other species is provided. An obligate human parasite evolutionary deprived of a substantial portion of its coding capacity is selected and genetic information about it is provided. By comparing the genetic information at least one open reading frame (ORF) common to the microorganism and the human parasite is identified, which codes for a protein (c) showing similarity with a hypothetical protein from other microorganism species. By introduction of a mutation in the ORF a mutated ORF is produced. The pathogenicity of the mutated pathogenic organism is assessed and compared with that of the corresponding non-mutated pathogenic organism. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102575296-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011019874-A1 |
| priorityDate |
2003-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |