abstract |
The present invention provides an agent obtainable by culturing a chondrocyte capable of hypertrophication in a differentiation agent producing medium, wherein the differentiation agent producing medium comprises at least one conventional osteoblast differentiation component selected from the group consisting of glucocorticoid, β-glycerophosphate and ascorbic acid. The differentiation agent producing medium may comprise all of glucocorticoid, β-glycerophosphate and ascorbic acid. |