Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f841589e51924dde33e7f068551ea71d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0fe351e8fb5cf814992fede294a21604 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-11 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-065 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0497 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0489 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-2208 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G79-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B59-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G61-12 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B59-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F5-06 |
filingDate |
2004-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd4c560c3e6a89d081daf61fd670f089 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a0953456fd863d0bdb3fc9bc8e5599b4 |
publicationDate |
2007-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2007155976-A1 |
titleOfInvention |
Prosthetic groups useful in the synthesis of radiopharmaceutical compounds |
abstract |
The present invention relates to compositions and methods for preparing radiopharmaceutical compounds in high chemical-purity and isotopic-purity. The present invention provides polymer-bound precursors to radiopharmaceutical compounds that can be converted to radiopharmaceutical compounds in one step. In a preferred embodiment, a radiopharmaceutical precursor is bound to a polymeric support via a prosthetic group comprising an alkenyl-tin bond. The radiopharmaceutical precursor is converted to a radiopharmaceutical compound in one step involving cleavage of the alkenyl-tin bond and incorporation of a radioisotope to form the radiopharmaceutical compound. Importantly, the polymeric support containing the toxic tin by-product can be easily removed from the radiopharmaceutical compound by filtration. The present invention can be used to install a large number of different radioisotopes. In a preferred embodiment, the radioisotope is 211 At, 123 I or 131 I. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2795694-C2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11363709-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11286172-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104470547-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9550704-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013176522-A1 |
priorityDate |
2003-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |