| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_33b53b5ea8e978d94f28885ddbb1b798
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e7bfdac5e9641ec5260cd605d227ad3a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_09e7e9b3d84ccde25c086c58c8f1bed2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2cc7598de4ef61941664eedaca3ca04e |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-98 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-573
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-542
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-543 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-06 |
| filingDate |
2006-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd2b9e57fe104805a97c154cdb835039
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c9b69a169dfd112350206ade779eabe
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c19366f819c46e3584fdd7239c5765f5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e44d0b9c0b110a9fbe25f22806e3c6fc |
| publicationDate |
2007-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2007154990-A1 |
| titleOfInvention |
Assays for identifying inhibitors of fatty acid amide hydrolase |
| abstract |
Assays for screening compounds suspected of binding fatty acid amide hydrolase (FAAH) using scintillation proximity assay (SPA) technology are described. The assays utilize the interactions of reversible inhibitors such as [ 3 H]—R(+)-methanandamide (MAEA) and membrane-associated FAAH, such as FAAH-containing microsomes, to evaluate the displacement activity of candidate FAAH inhibitors. The assays are specific for FAAH where FAAH binding compounds can be detected. Various embodiments of the assay have been validated and demonstrated to be simple, sensitive and amenable to high-throughput screening. Kits for performing the assays are also disclosed. |
| priorityDate |
2005-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |