http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007149604-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_459549086df37b5bed0003502de7e7aa |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-42 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-405 |
filingDate | 2003-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_55de81ac6b585dea5183dc9abe0727ff http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3907134b2e6f9d65fcc8cd3c7b50460c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2752ff516927cb06cafb4d3e2534a9cb |
publicationDate | 2007-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2007149604-A1 |
titleOfInvention | Novel method for preparation of crystalline perindopril erbumine |
abstract | A process for preparation of crystalline perindopril erbumine of formula (II) n n nwhich exhibits the X-ray (powder) diffraction pattern like that shown in FIG. 2 n nThe process comprises reacting a solution of perindopril of formula (I), n nin a solvent selected from N,N-dimethylformamide, dimethyl acetals of lower aliphatic aldehydes, dimethyl ketals of lower aliphatic ketones and 1,2-dialkoxyethane with tertiary butylamine and crystallization of the erbumine salt thus obtained by heating the reaction mixture to reflux, filtering hot, cooling gradually to 20° C. to 30° C., and further cooling to 0° C. to 15° C. for 30 minutes to 1 hour and finally filtering off and drying the crystals. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2014086792-A1 |
priorityDate | 2003-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 492.