| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cb8f3eba86915d967beefc175437273a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-342
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4748 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 |
| filingDate |
2006-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6440b4e70434364442313e7552a7f23f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa69b377da4ccb41093bbfdf4f3002d8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_54d8da81a49c9207ee896fa66b5a01a3 |
| publicationDate |
2007-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2007148662-A1 |
| titleOfInvention |
Prostate-specific membrane antigen |
| abstract |
This invention provides an isolated mammalian nucleic acid molecule encoding a mammalian prostate-specific membrane antigen. This invention also provides prostate-specific membrane nucleic acid of at least 15 nucleotides capable of specifically hybridizing with a sequence of a nucleic acid molecule encoding a mammalian prostate-specific membrane antigen. This invention further provides vector and vector host expression system for the prostate-specific membrane antigen. This invention also provides methods to identify ligands which bind to the prostate-specific membrane antigen, to generate antibody against a complete prostate-specific membrane antigen or a portion of the antigen. This invention further provides purified prostate-specific membrane antigen. This invention provides a therapeutic agent comprising an antibody directed against to prostate-specific membrane antigen and a cytotoxic agent conjugated thereto. This invention also provides a method of imaging prostate cancer and an immunoassay for measuring the amount of the prostate-specific membrane antigen in a biological simple. This invention further provides transgenic nonhuman mammal which comprises the isolated nucleic acid molecule encoding a mammalian prostate-specific membrane antigen. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10471160-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10898596-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10912840-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9782493-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11083710-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010324008-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011189093-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10485878-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11717514-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9242012-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10517956-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10517957-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9695248-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8114965-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10828282-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004033229-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11155800-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10624969-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10624970-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10624971-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008286284-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8470330-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9713649-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11045564-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11369590-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8907058-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9636413-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10646581-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11298341-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10046054-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11318121-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9193763-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10188759-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10398791-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011165081-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10557128-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10406240-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10918741-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11504357-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9951324-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7850971-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-RE43586-E |
| priorityDate |
1992-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |